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2rs7
From Proteopedia
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{{STRUCTURE_2rs7| PDB=2rs7 | SCENE= }} | {{STRUCTURE_2rs7| PDB=2rs7 | SCENE= }} | ||
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===Solution structure of the second dsRBD from RNA helicase A=== | ===Solution structure of the second dsRBD from RNA helicase A=== | ||
| + | {{ABSTRACT_PUBMED_22454253}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/DHX9_MOUSE DHX9_MOUSE]] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[2rs7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS7 OCA]. | [[2rs7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS7 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022454253</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: RNA helicase]] | [[Category: RNA helicase]] | ||
Revision as of 06:52, 16 October 2013
Contents |
Solution structure of the second dsRBD from RNA helicase A
Template:ABSTRACT PUBMED 22454253
Function
[DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).
About this Structure
2rs7 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.
Reference
- Nagata T, Tsuda K, Kobayashi N, Shirouzu M, Kigawa T, Guntert P, Yokoyama S, Muto Y. Solution structures of the double-stranded RNA-binding domains from RNA helicase A. Proteins. 2012 Jun;80(6):1699-706. doi: 10.1002/prot.24059. Epub 2012 Mar 27. PMID:22454253 doi:http://dx.doi.org/10.1002/prot.24059
Categories: Mus musculus | RNA helicase | Inoue, M. | Kigawa, T. | Muto, Y. | Nagata, T. | Shirouzu, M. | Terada, T. | Tsuda, K. | Yokoyama, S. | Double-stranded rna binding domain | Dsrbd | Dsrm | Hydrolase | National project on protein structural and functional analyse | Nppsfa | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic
