Cholesterol oxidase

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{{STRUCTURE_1coy| PDB=1coy | SIZE=400| SCENE= |right|CAPTION=Cholesterol oxidase complex with steroid substrate , [[1coy]] }}
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Revision as of 11:39, 14 March 2012

Template:STRUCTURE 1coy

Cholesterol oxidase (COX) catalyzes the conversion of cholesterol and molecular oxygen to Colest-4-en-3-one and hydrogen peroxide. COX uses FAD as a cofactor. COX I binds FAD non-covalently whereas COX II binds FAD covalently.

3D structure of cholesterol oxidase

1cox, 1i19 – BsCOX – Brevibacterium sterolicum
1b4v, 1mxt, 1n1p, 1n4u, 1n4v, 1n4w, 2gew – StCOX – Streptomyces
1b8s, 1cbo, 1cc2, 1ijh, 3b6d, 3cnj, 3gyi, 3gyj – StCOX (mutant)
3js8 – COX – Chromobacterium

Cholesterol oxidase complex

1coy – BsCOX + steroid
3b3r - StCOX (mutant) + glycerol

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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