3uzz
From Proteopedia
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{{STRUCTURE_3uzz| PDB=3uzz | SCENE= }} | {{STRUCTURE_3uzz| PDB=3uzz | SCENE= }} | ||
===Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and delta4-androstenedione=== | ===Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and delta4-androstenedione=== | ||
| + | {{ABSTRACT_PUBMED_22437839}} | ||
==About this Structure== | ==About this Structure== | ||
[[3uzz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZZ OCA]. | [[3uzz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZZ OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022437839</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, M.]] | [[Category: Chen, M.]] | ||
Revision as of 04:42, 27 June 2012
Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and delta4-androstenedione
Template:ABSTRACT PUBMED 22437839
About this Structure
3uzz is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chen M, Drury JE, Christianson DW, Penning TM. Conversion of human steroid 5beta-reductase (AKR1D1) into 3beta-hydroxysteroid dehydrogenase by single point mutation E120H: example of perfect enzyme engineering. J Biol Chem. 2012 May 11;287(20):16609-22. Epub 2012 Mar 20. PMID:22437839 doi:10.1074/jbc.M111.338780
