2vuq

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[[Image:2vuq.png|left|200px]]
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==Crystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolution==
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<StructureSection load='2vuq' size='340' side='right' caption='[[2vuq]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2vuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUQ OCA]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vuq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vuq RCSB], [http://www.ebi.ac.uk/pdbsum/2vuq PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The tRNA(Gly)/Glycyl-tRNA synthetase system belongs to the so called 'class II' in which tRNA identity elements consist of relative few and simple motifs, as compared to 'class I' where the tRNA determinants are more complicated and spread over different parts of the tRNA, mostly including the anticodon. The determinants from 'class II' although, are located in the aminoacyl stem and sometimes include the discriminator base. There exist predominant structure differences for the Glycyl-tRNA-synthetases and for the tRNA(Gly) identity elements comparing eucaryotic/archaebacterial and eubacterial systems. We focus on comparative X-ray structure analysis of tRNA(Gly) acceptor stem microhelices from different organisms. Here, we report the X-ray structure of the human tRNA(Gly) microhelix isoacceptor G9990 at 1.18A resolution. Superposition experiments to another human tRNA(Gly) microhelix and a detailed comparison of the RNA hydration patterns show a great number of water molecules with identical positions in both RNAs. This is the first structure comparison of hydration layers from two isoacceptor tRNA microhelices with a naturally occurring base pair exchange.
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Crystal structure of the human tRNAGly microhelix isoacceptor G9990 at 1.18A resolution.,Eichert A, Perbandt M, Schreiber A, Furste JP, Betzel C, Erdmann VA, Forster C Biochem Biophys Res Commun. 2009 Mar 13;380(3):503-7. Epub 2009 Jan 27. PMID:19284994<ref>PMID:19284994</ref>
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The line below this paragraph, containing "STRUCTURE_2vuq", creates the "Structure Box" on the page.
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_2vuq| PDB=2vuq | SCENE= }}
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===Crystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolution===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_19284994}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 19284994 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_19284994}}
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==About this Structure==
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[[2vuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUQ OCA].
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==Reference==
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<ref group="xtra">PMID:019284994</ref><references group="xtra"/>
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[[Category: Betzel, C.]]
[[Category: Betzel, C.]]
[[Category: Eichert, A.]]
[[Category: Eichert, A.]]

Revision as of 08:37, 7 May 2014

Crystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolution

2vuq, resolution 1.18Å

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