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4a2j
From Proteopedia
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{{STRUCTURE_4a2j| PDB=4a2j | SCENE= }} | {{STRUCTURE_4a2j| PDB=4a2j | SCENE= }} | ||
===PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids=== | ===PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids=== | ||
| + | {{ABSTRACT_PUBMED_22535964}} | ||
==About this Structure== | ==About this Structure== | ||
[[4a2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2J OCA]. | [[4a2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2J OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022535964</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bosch, R.]] | [[Category: Bosch, R.]] | ||
Revision as of 06:54, 4 July 2012
PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids
Template:ABSTRACT PUBMED 22535964
About this Structure
4a2j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lusher SJ, Raaijmakers HC, Vu-Pham D, Kazemier B, Bosch R, McGuire R, Azevedo R, Hamersma H, Dechering K, Oubrie A, van Duin M, de Vlieg J. X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11beta-Substituted Steroids. J Biol Chem. 2012 Jun 8;287(24):20333-43. Epub 2012 Apr 25. PMID:22535964 doi:10.1074/jbc.M111.308403
