1aix

(Difference between revisions)

Revision as of 08:23, 26 July 2012

1aix is a 3 chain structure of Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Bode W, Turk D, Karshikov A. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci. 1992 Apr;1(4):426-71. PMID:1304349

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 [[Image:1aix.png|left|200px]]
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 {{STRUCTURE_1aix|  PDB=1aix  |  SCENE=  }}
 ===HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROVAL===
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