4app

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m (Protected "4app" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4app.jpg|left|200px]]
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The entry 4app is ON HOLD until Paper Publication
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{{STRUCTURE_4app| PDB=4app | SCENE= }}
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Authors: Knighton, D.R., Deng, Y., Wang, C., Guo, C., McAlpine, I., Zhang, J., Kephart, S., Johnson, C., Li, H., Bouzida, D., Yang, A., Dong, L., Marakovits, J., Tikhe, J., Richardson, P., Guo, L., Kania, R., Edwards, M., Kraynov, E., Christensen, J., Piraino, J., Lee, J., Dagostino, E., Del-Carmen, C., Smeal, T., Murray, B.
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===Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide===
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Description: Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide
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{{ABSTRACT_PUBMED_22554206}}
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==About this Structure==
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[[4app]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4APP OCA].
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==Reference==
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<ref group="xtra">PMID:022554206</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Bouzida, D.]]
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[[Category: Christensen, J.]]
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[[Category: Dagostino, E.]]
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[[Category: Del-Carmen, C.]]
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[[Category: Deng, Y L.]]
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[[Category: Dong, L.]]
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[[Category: Edwards, M P.]]
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[[Category: Guo, C.]]
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[[Category: Guo, L C.]]
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[[Category: Johnson, M C.]]
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[[Category: Kania, R.]]
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[[Category: Kephart, S.]]
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[[Category: Knighton, D D.]]
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[[Category: Kraynov, E.]]
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[[Category: Lee, J.]]
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[[Category: Li, H.]]
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[[Category: Marakovits, J.]]
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[[Category: Mcalpine, I.]]
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[[Category: Murray, B W.]]
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[[Category: Piraino, J.]]
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[[Category: Richardson, P.]]
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[[Category: Smeal, T.]]
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[[Category: Tikhe, J.]]
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[[Category: Wang, C.]]
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[[Category: Yang, A.]]
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[[Category: Zhang, J.]]
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[[Category: Protein kinase]]
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[[Category: Transferase]]

Revision as of 07:38, 6 June 2012

Image:4app.jpg

Template:STRUCTURE 4app

Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide

Template:ABSTRACT PUBMED 22554206

About this Structure

4app is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Guo C, McAlpine I, Zhang J, Knighton DD, Kephart S, Johnson MC, Li H, Bouzida D, Yang A, Dong L, Marakovits J, Tikhe J, Richardson P, Guo LC, Kania R, Edwards MP, Kraynov E, Christensen J, Piraino J, Lee J, Dagostino E, Del-Carmen C, Deng YL, Smeal T, Murray BW. Discovery of Pyrroloaminopyrazoles as Novel PAK Inhibitors. J Med Chem. 2012 May 24;55(10):4728-39. Epub 2012 May 14. PMID:22554206 doi:10.1021/jm300204j

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OCA

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