4dru
From Proteopedia
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| - | [[Image:4dru. | + | [[Image:4dru.png|left|200px]] |
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{{STRUCTURE_4dru| PDB=4dru | SCENE= }} | {{STRUCTURE_4dru| PDB=4dru | SCENE= }} | ||
===HCV NS5B in complex with macrocyclic INDOLE INHIBITOR=== | ===HCV NS5B in complex with macrocyclic INDOLE INHIBITOR=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_22473861}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 22473861 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_22473861}} | {{ABSTRACT_PUBMED_22473861}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4dru]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRU OCA]. | + | [[4dru]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRU OCA]. |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
Revision as of 01:26, 27 July 2012
Contents |
HCV NS5B in complex with macrocyclic INDOLE INHIBITOR
Template:ABSTRACT PUBMED 22473861
About this Structure
4dru is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Cummings MD, Lin TI, Hu L, Tahri A, McGowan D, Amssoms K, Last S, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, Fransen E, Cleiren E, van der Helm L, Fanning G, Van Emelen K, Nyanguile O, Simmen K, Raboisson P, Vendeville S. Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties. Angew Chem Int Ed Engl. 2012 Mar 30. doi: 10.1002/anie.201200110. PMID:22473861 doi:10.1002/anie.201200110
