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Sandbox SouthUniversity3
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The drug raltegravir (Isentress)is the first drug that has made its way to market that acts as an inhibitor of HIV-integrase. It is shown <scene name='Sandbox_SouthUniversity3/Isentress_spacefill/1'>here</scene> displayed in a space filling representation.It is easier to see the functional groups displayed as <scene name='Sandbox_SouthUniversity3/Isentress_sticks/1'>sticks</scene> | The drug raltegravir (Isentress)is the first drug that has made its way to market that acts as an inhibitor of HIV-integrase. It is shown <scene name='Sandbox_SouthUniversity3/Isentress_spacefill/1'>here</scene> displayed in a space filling representation.It is easier to see the functional groups displayed as <scene name='Sandbox_SouthUniversity3/Isentress_sticks/1'>sticks</scene> | ||
| - | Note the 3 oxygen atoms labeled <scene name='Sandbox_SouthUniversity3/Isentress_oxy_label/2'>here</scene>. They are a vital part of the structure, since they bind (chelate) to 2 magnesium ions within the enzyme. | + | Note the 3 oxygen atoms labeled <scene name='Sandbox_SouthUniversity3/Isentress_oxy_label/2'>here</scene>. They are a vital part of the structure, since they bind (chelate) to 2 magnesium ions within the enzyme. The oxygen atoms are highlighted here as <scene name='Sandbox_SouthUniversity3/Mg_atoms/1'>green spheres</scene> |
</StructureSection> | </StructureSection> | ||
Revision as of 14:40, 18 April 2012
==Integrase as an anti-HIV drug target==
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