3kw7

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[[Image:3kw7.png|left|200px]]
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==Crystal structure of LacB from Trametes sp. AH28-2==
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<StructureSection load='3kw7' size='340' side='right' caption='[[3kw7]], [[Resolution|resolution]] 3.44&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3kw7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trametes Trametes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KW7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kw7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kw7 RCSB], [http://www.ebi.ac.uk/pdbsum/3kw7 PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/3kw7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Fungal laccases are oxidoreductases that belong to the multinuclear copper-containing oxidases. They are able to oxidize a wide range of substrates, preferably phenolic compounds, which makes them suitable for employment in the bioremediation of soil and water as well as in other biotechnological applications. Here, the structural analysis of natural laccase B (LacB) from Trametes sp. AH28-2 is presented. This structure provides the opportunity to study the natural post-translational modifications of the enzyme. The overall fold shows a high homology to those of previously analyzed laccases with known three-dimensional structure. However, LacB contains a new structural element, a protruding loop near the substrate-binding site, compared with the previously reported laccase structures. This unique structural feature may be involved in modulation of the substrate recognition of LacB.
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Structure of native laccase B from Trametes sp. AH28-2.,Ge H, Gao Y, Hong Y, Zhang M, Xiao Y, Teng M, Niu L Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt, 3):254-8. Epub 2010 Feb 23. PMID:20208154<ref>PMID:20208154</ref>
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The line below this paragraph, containing "STRUCTURE_3kw7", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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-->
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{{STRUCTURE_3kw7| PDB=3kw7 | SCENE= }}
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===Crystal structure of LacB from Trametes sp. AH28-2===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_20208154}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 20208154 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_20208154}}
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==About this Structure==
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[[3kw7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trametes Trametes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW7 OCA].
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==Reference==
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<ref group="xtra">PMID:020208154</ref><references group="xtra"/>
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[[Category: Laccase]]
[[Category: Laccase]]
[[Category: Trametes]]
[[Category: Trametes]]

Revision as of 09:40, 21 May 2014

Crystal structure of LacB from Trametes sp. AH28-2

3kw7, resolution 3.44Å

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