4ef0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4ef0| PDB=4ef0 | SCENE= }}
 +
===Crystal Structure of the first catalytic domain of protein disulfide isomerase P5===
-
The entry 4ef0 is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN]] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref>
-
Authors: Vinaik, R., Kozlov, G., Gehring, K.
+
==About this Structure==
 +
[[4ef0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EF0 OCA].
-
Description: Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Protein disulfide-isomerase]]
 +
[[Category: Gehring, K.]]
 +
[[Category: Kozlov, G.]]
 +
[[Category: Vinaik, R.]]
 +
[[Category: Bip]]
 +
[[Category: Disulfide bond isomerization]]
 +
[[Category: Endoplasmic reticulum]]
 +
[[Category: Isomerase]]
 +
[[Category: Thioredoxin-like fold]]

Revision as of 01:47, 4 April 2013

Template:STRUCTURE 4ef0

Contents

Crystal Structure of the first catalytic domain of protein disulfide isomerase P5

Function

[PDIA6_HUMAN] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.[1] [2]

About this Structure

4ef0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Jordan PA, Stevens JM, Hubbard GP, Barrett NE, Sage T, Authi KS, Gibbins JM. A role for the thiol isomerase protein ERP5 in platelet function. Blood. 2005 Feb 15;105(4):1500-7. Epub 2004 Oct 5. PMID:15466936 doi:10.1182/blood-2004-02-0608
  2. ↑ Kikuchi M, Doi E, Tsujimoto I, Horibe T, Tsujimoto Y. Functional analysis of human P5, a protein disulfide isomerase homologue. J Biochem. 2002 Sep;132(3):451-5. PMID:12204115

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ef0"
Personal tools