1mh1
From Proteopedia
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==Overview== | ==Overview== | ||
| - | The crystal structure of human rac1, a member of the rho family of small | + | The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family. |
==About this Structure== | ==About this Structure== | ||
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[[Category: Dodson, G.]] | [[Category: Dodson, G.]] | ||
[[Category: Hirshberg, M.]] | [[Category: Hirshberg, M.]] | ||
| - | [[Category: Stockley, R | + | [[Category: Stockley, R W.]] |
| - | [[Category: Webb, M | + | [[Category: Webb, M R.]] |
[[Category: GNP]] | [[Category: GNP]] | ||
[[Category: MG]] | [[Category: MG]] | ||
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[[Category: small g-protein]] | [[Category: small g-protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:55:05 2008'' |
Revision as of 11:55, 21 February 2008
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SMALL G-PROTEIN
Overview
The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family.
About this Structure
1MH1 is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.
Reference
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:9033596
Page seeded by OCA on Thu Feb 21 13:55:05 2008
Categories: Homo sapiens | Single protein | Dodson, G. | Hirshberg, M. | Stockley, R W. | Webb, M R. | GNP | MG | Gtp-binding | Gtpase | Ras super family | Rho family | Small g-protein
