4eo8

From Proteopedia

proteopedia linkproteopedia link

Revision as of 08:55, 25 April 2012 (edit) OCA (Talk | contribs) m (Protected "4eo8" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 05:49, 27 June 2012 (edit) (undo) OCA (Talk | contribs) Next diff →
Line 1:		Line 1:
-	'''Unreleased structure'''	+	[[Image:4eo8.jpg|left|200px]]
-	The entry 4eo8 is ON HOLD	+	{{STRUCTURE_4eo8| PDB=4eo8 | SCENE= }}
-	Authors: Appleby, T.C., Canales, E., Watkins, W.J.	+	===HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres===
-	Description: HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres	+	{{ABSTRACT_PUBMED_22664130}}
		+
		+	==About this Structure==
		+	[[4eo8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO8 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022664130</ref><references group="xtra"/>
		+	[[Category: RNA-directed RNA polymerase]]
		+	[[Category: Viruses]]
		+	[[Category: Appleby, T C.]]
		+	[[Category: Canales, E.]]
		+	[[Category: Watkins, W J.]]
		+	[[Category: Hcv]]
		+	[[Category: Ns5b]]
		+	[[Category: Polymerase inhibitor]]
		+	[[Category: Rna]]
		+	[[Category: Rna polymerase]]
		+	[[Category: Rna-dependent rna polymerase]]
		+	[[Category: Thumb site 2 inhibitor]]
		+	[[Category: Transferase-transferase inhibitor complex]]

---

Revision as of 05:49, 27 June 2012

Template:STRUCTURE 4eo8

HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres

Template:ABSTRACT PUBMED 22664130

About this Structure

4eo8 is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

• Canales E, Carlson JS, Appleby T, Fenaux M, Lee J, Tian Y, Tirunagari N, Wong M, Watkins WJ. Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4288-92. Epub 2012 May 17. PMID:22664130 doi:10.1016/j.bmcl.2012.05.025