3ujm

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[[Image:3ujm.jpg|left|200px]]
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==Crystal structure of the NTF2-like domain of the Drosophila melanogaster Rasputin protein==
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<StructureSection load='3ujm' size='340' side='right' caption='[[3ujm]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ujm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UJM FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene><br>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rin, CG9412 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ujm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ujm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ujm RCSB], [http://www.ebi.ac.uk/pdbsum/3ujm PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7A resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised of a beta-sheet and three alpha-helices forming a cone-like shape. However, known binding sites for RanGDP and FxFG containing peptides show electrostatic and steric differences compared to nuclear transport factor 2. A HEPES molecule bound in the structure suggests a new, and possibly physiologically relevant, ligand binding site.
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Crystal structure of the Rasputin NTF2-like domain from Drosophila melanogaster.,Vognsen T, Kristensen O Biochem Biophys Res Commun. 2012 Mar 30;420(1):188-92. Epub 2012 Mar 3. PMID:22414690<ref>PMID:22414690</ref>
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The line below this paragraph, containing "STRUCTURE_3ujm", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3ujm| PDB=3ujm | SCENE= }}
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===Crystal structure of the NTF2-like domain of the Drosophila melanogaster Rasputin protein===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22414690}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22414690 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22414690}}
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==About this Structure==
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[[3ujm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UJM OCA].
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==Reference==
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<ref group="xtra">PMID:022414690</ref><references group="xtra"/>
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Kristensen, O.]]
[[Category: Kristensen, O.]]

Revision as of 06:38, 5 June 2014

Crystal structure of the NTF2-like domain of the Drosophila melanogaster Rasputin protein

3ujm, resolution 2.74Å

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