3tvj
From Proteopedia
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===Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold=== | ===Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22511776}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22511776 is the PubMed ID number. | ||
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==About this Structure== | ==About this Structure== | ||
[[3tvj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Schistocerca_gregaria Schistocerca gregaria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TVJ OCA]. | [[3tvj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Schistocerca_gregaria Schistocerca gregaria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TVJ OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022511776</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mannan-binding lectin-associated serine protease-2]] | [[Category: Mannan-binding lectin-associated serine protease-2]] | ||
Revision as of 08:11, 9 May 2012
Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold
Template:ABSTRACT PUBMED 22511776
About this Structure
3tvj is a 3 chain structure with sequence from Homo sapiens and Schistocerca gregaria. Full crystallographic information is available from OCA.
Reference
- Heja D, Harmat V, Fodor K, Wilmanns M, Dobo J, Kekesi KA, Zavodszky P, Gal P, Pal G. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease (MASP)-1 and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2. J Biol Chem. 2012 Apr 16. PMID:22511776 doi:10.1074/jbc.M112.354332
