4djz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:4djz. | + | [[Image:4djz.png|left|200px]] |
<!-- | <!-- | ||
| Line 11: | Line 11: | ||
===Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold=== | ===Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22511776}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22511776 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_22511776}} | ||
==About this Structure== | ==About this Structure== | ||
[[4djz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Schistocerca_gregaria Schistocerca gregaria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJZ OCA]. | [[4djz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Schistocerca_gregaria Schistocerca gregaria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJZ OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022511776</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Schistocerca gregaria]] | [[Category: Schistocerca gregaria]] | ||
Revision as of 08:20, 9 May 2012
Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold
Template:ABSTRACT PUBMED 22511776
About this Structure
4djz is a 6 chain structure with sequence from Homo sapiens and Schistocerca gregaria. Full crystallographic information is available from OCA.
Reference
- Heja D, Harmat V, Fodor K, Wilmanns M, Dobo J, Kekesi KA, Zavodszky P, Gal P, Pal G. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease (MASP)-1 and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2. J Biol Chem. 2012 Apr 16. PMID:22511776 doi:10.1074/jbc.M112.354332
