3tvj
From Proteopedia
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===Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold=== | ===Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold=== | ||
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Revision as of 04:28, 27 June 2012
Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold
Template:ABSTRACT PUBMED 22511776
About this Structure
3tvj is a 3 chain structure with sequence from Homo sapiens and Schistocerca gregaria. Full crystallographic information is available from OCA.
Reference
- Heja D, Harmat V, Fodor K, Wilmanns M, Dobo J, Kekesi KA, Zavodszky P, Gal P, Pal G. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease (MASP)-1 and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2. J Biol Chem. 2012 Apr 16. PMID:22511776 doi:10.1074/jbc.M112.354332
