This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wwl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1wwl.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_1wwl", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_1wwl| PDB=1wwl | SCENE= }}
{{STRUCTURE_1wwl| PDB=1wwl | SCENE= }}
- 
===Crystal structure of CD14===
===Crystal structure of CD14===
 +
{{ABSTRACT_PUBMED_15644310}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/CD14_MOUSE CD14_MOUSE]] Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).
-
The line below this paragraph, {{ABSTRACT_PUBMED_15644310}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 15644310 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15644310}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:015644310</ref><references group="xtra"/>
+
<ref group="xtra">PMID:015644310</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Jin, M S.]]
[[Category: Jin, M S.]]

Revision as of 08:19, 23 April 2014

Template:STRUCTURE 1wwl

Contents

Crystal structure of CD14

Template:ABSTRACT PUBMED 15644310

Function

[CD14_MOUSE] Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).

About this Structure

1wwl is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Kim JI, Lee CJ, Jin MS, Lee CH, Paik SG, Lee H, Lee JO. Crystal structure of CD14 and its implications for lipopolysaccharide signaling. J Biol Chem. 2005 Mar 25;280(12):11347-51. Epub 2005 Jan 10. PMID:15644310 doi:10.1074/jbc.M414607200

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wwl"
Personal tools