2w1h
From Proteopedia
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{{STRUCTURE_2w1h| PDB=2w1h | SCENE= }} | {{STRUCTURE_2w1h| PDB=2w1h | SCENE= }} | ||
===Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity=== | ===Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity=== | ||
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{{ABSTRACT_PUBMED_19143567}} | {{ABSTRACT_PUBMED_19143567}} | ||
Revision as of 16:53, 27 July 2012
Contents |
Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity
Template:ABSTRACT PUBMED 19143567
About this Structure
2w1h is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Berdini, V. | Boulstridge, J A. | Brien, M A.O. | Carr, M G. | Cross, D M. | Curry, J. | Devine, L A. | Early, T R. | Fazal, L. | Gill, A L. | Heathcote, M. | Howard, S. | Maman, S. | Matthews, J E. | Mcmenamin, R L. | Navarro, E F. | Rees, D C. | Reilly, M O. | Reule, M. | Tisi, D. | Vinkovic, M. | Williams, G. | Wyatt, P G. | Atp-binding | Cell cycle | Cell division | Fragment screening | Kinase | Mitosis | Nucleotide-binding | Phosphoprotein | Serine/threonine-protein kinase | Structure based drug design | Transferase
