4drk

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Revision as of 05:16, 23 May 2012

Template:STRUCTURE 4drk

EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid

Template:ABSTRACT PUBMED 22455444

About this Structure

4drk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Gopalakrishnan R, Kozany C, Gaali S, Kress C, Hoogeland B, Bracher A, Hausch F. Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52. J Med Chem. 2012 May 10;55(9):4114-22. Epub 2012 Apr 19. PMID:22455444 doi:10.1021/jm201746x