Nuclear receptor coactivator
From Proteopedia
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[[2c52]] – hNCOA1 residues 920-970 + CREB-binding protein - NMR<br /> | [[2c52]] – hNCOA1 residues 920-970 + CREB-binding protein - NMR<br /> | ||
[[1oj5]] – NCOA1A Pas-B domain + signal transducer and activator of transcription peptide - mouse | [[1oj5]] – NCOA1A Pas-B domain + signal transducer and activator of transcription peptide - mouse | ||
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Revision as of 11:37, 17 May 2012
Template:STRUCTURE 1v95 Nuclear receptor coactivator (NCOA) is a protein recruited by nuclear receptors in order to enhance or repress DNA transcription. NCOA are involved in coactivation with transcription factors. NCOA1 shows histone acetyltransferase activity and is required for steroid hormone response. NCOA2 is a DNA transcription coactivator with glucocorticoid receptor. NCOA3 shows histone acetyltransferase activity.
3D structures of nuclear receptor coactivator
1v95 – hNCOA5 – human - NMR
1kbh – hNCOA + CREB-binding protein - NMR
2c52 – hNCOA1 residues 920-970 + CREB-binding protein - NMR
1oj5 – NCOA1A Pas-B domain + signal transducer and activator of transcription peptide - mouse
