3sfc

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[[Image:3sfc.png|left|200px]]
[[Image:3sfc.png|left|200px]]
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{{STRUCTURE_3sfc| PDB=3sfc | SCENE= }}
{{STRUCTURE_3sfc| PDB=3sfc | SCENE= }}
===Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors===
===Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors===
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{{ABSTRACT_PUBMED_21840218}}
{{ABSTRACT_PUBMED_21840218}}
==About this Structure==
==About this Structure==
[[3sfc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFC OCA].
[[3sfc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFC OCA].
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==See Also==
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*[[Renin|Renin]]
==Reference==
==Reference==

Revision as of 16:27, 20 October 2012

Template:STRUCTURE 3sfc

Contents

Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors

Template:ABSTRACT PUBMED 21840218

About this Structure

3sfc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Scheiper B, Matter H, Steinhagen H, Bocskei Z, Fleury V, McCort G. Structure-based optimization of potent 4- and 6-azaindole-3-carboxamides as renin inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5480-6. Epub 2011 Jul 6. PMID:21840218 doi:10.1016/j.bmcl.2011.06.114
  • Scheiper B, Matter H, Steinhagen H, Stilz U, Bocskei Z, Fleury V, McCort G. Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6268-72. Epub 2010 Aug 21. PMID:20850300 doi:10.1016/j.bmcl.2010.08.092

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