4ere
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | [[Image:4ere. | + | [[Image:4ere.png|left|200px]] |
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_4ere", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_4ere| PDB=4ere | SCENE= }} | {{STRUCTURE_4ere| PDB=4ere | SCENE= }} | ||
===crystal structure of MDM2 (17-111) in complex with compound 23=== | ===crystal structure of MDM2 (17-111) in complex with compound 23=== | ||
- | |||
- | <!-- | ||
- | The line below this paragraph, {{ABSTRACT_PUBMED_22524527}}, adds the Publication Abstract to the page | ||
- | (as it appears on PubMed at http://www.pubmed.gov), where 22524527 is the PubMed ID number. | ||
- | --> | ||
{{ABSTRACT_PUBMED_22524527}} | {{ABSTRACT_PUBMED_22524527}} | ||
Revision as of 07:24, 2 January 2013
crystal structure of MDM2 (17-111) in complex with compound 23
Template:ABSTRACT PUBMED 22524527
About this Structure
4ere is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rew Y, Sun D, Gonzalez-Lopez De Turiso F, Bartberger MD, Beck HP, Canon J, Chen A, Chow D, Deignan J, Fox BM, Gustin D, Huang X, Jiang M, Jiao X, Jin L, Kayser F, Kopecky DJ, Li Y, Lo MC, Long AM, Michelsen K, Oliner JD, Osgood T, Ragains M, Saiki AY, Schneider S, Toteva M, Yakowec P, Yan X, Ye Q, Yu D, Zhao X, Zhou J, Medina JC, Olson SH. Structure-Based Design of Novel Inhibitors of the MDM2-p53 Interaction. J Med Chem. 2012 May 9. PMID:22524527 doi:10.1021/jm300354j