This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Amyloid precursor protein
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{ | + | {{STRUCTURE_1mwp| PDB=1mwp | SIZE=400| SCENE= |right| CAPTION=Human amyloid precursor protein E1-dimer domain complex with butane diol, sulfate and acetate, [[1mwp]] }} |
'''Amyloid precursor protein''' (APP) is thought to regulate transcription. For detailed discussion see [[Human APP]] and [[Human APP Intracellular Domain Complex with Fe65-PTB2]]. | '''Amyloid precursor protein''' (APP) is thought to regulate transcription. For detailed discussion see [[Human APP]] and [[Human APP Intracellular Domain Complex with Fe65-PTB2]]. | ||
Revision as of 11:00, 11 December 2012
Amyloid precursor protein (APP) is thought to regulate transcription. For detailed discussion see Human APP and Human APP Intracellular Domain Complex with Fe65-PTB2.
3D structures of amyloid precursor protein
Update May 2012
3nyj, 3nyl, 3umh, 3umi, 3umk – hAPP E2 domain – human
3ktm – hAPP residues 18-190
1z0q, 2beg – hAPP β-peptide – NMR
1ze7, 2bp4 – hAPP zinc-binding domain – NMR
2fjz, 2fma - hAPP residues 133-189
1owt - hAPP residues 133-189 - NMR
1rw6 - hAPP residues 346-551
1tkn - hAPP residues 460-569 - NMR
1qyt, 1qwp, 1qxc - hAPP residues 25-35 – NMR
1mwp - hAPP heparin-binding domain
Amyloid precursor protein binary complex
1ze9 - hAPP zinc-binding domain + Zn – NMR
2fk1, 2fk2, 2fk3, 2fkl - hAPP residues 133-189 + Cu
3jti, 3gci – hAPP peptide + phospholipase A2
3l81 - hAPP peptide + AP-4 complex subunit μ-1
3ifl, 3ifn, 3ifo, 3ifp, 2r0w - hAPP peptide + antibody
2wk3 - hAPP residues 1-42 + insulin degrading enzyme
3dxc - hAPP residues 739-770 + Fe65-PTB2
3dxd, 3dxe - hAPP residues 739-770 (mutant) + Fe65-PTB2
2roz - hAPP peptide + Fe65 C terminal
2otk - hAPP residues 672-711 + ZAB3 affibody dimer - NMR
3l3t - hAPP residues 211-267 + mesotrypsin
3l33 - hAPP residues 290-341 + trypsin-3 (mutant)
