4aof
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:4aof.png|left|200px]] | [[Image:4aof.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_4aof", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_4aof| PDB=4aof | SCENE= }} | {{STRUCTURE_4aof| PDB=4aof | SCENE= }} | ||
===Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma=== | ===Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_22544264}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 22544264 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_22544264}} | {{ABSTRACT_PUBMED_22544264}} | ||
Revision as of 07:21, 11 July 2012
Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma
Template:ABSTRACT PUBMED 22544264
About this Structure
4aof is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Muller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. A selective inhibitor reveals PI3Kgamma dependence of T(H)17 cell differentiation. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. PMID:22544264 doi:10.1038/nchembio.957
Categories: Homo sapiens | Bantscheff, M. | Bell, K. | Bergamini, G. | Cansfield, A. | Doce, C. | Drewes, G. | Ellard, K. | Hirsch, E. | Hopf, C. | Leggate, D. | Mangano, R. | Mathieson, T. | Muller, K. | Neubauer, G. | Omahony, A. | Perrin, J. | Plavec, I. | Ramsden, N. | Rau, C. | Rausch, O. | Reinhard, F. | Rharbaoui, F. | Savitski, M M. | Shimamura, S. | Werner, T. | Transferase
