2b4g
From Proteopedia
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{{STRUCTURE_2b4g| PDB=2b4g | SCENE= }} | {{STRUCTURE_2b4g| PDB=2b4g | SCENE= }} | ||
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===dihydroorotate dehydrogenase=== | ===dihydroorotate dehydrogenase=== | ||
| + | {{ABSTRACT_PUBMED_18312275}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/Q57U83_9TRYP Q57U83_9TRYP]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |
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==About this Structure== | ==About this Structure== | ||
[[2b4g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4G OCA]. | [[2b4g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4G OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:018312275</ref><references group="xtra"/> | + | <ref group="xtra">PMID:018312275</ref><references group="xtra"/><references/> |
[[Category: Dihydroorotate dehydrogenase]] | [[Category: Dihydroorotate dehydrogenase]] | ||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
Revision as of 08:17, 23 April 2014
Contents |
dihydroorotate dehydrogenase
Template:ABSTRACT PUBMED 18312275
Function
[Q57U83_9TRYP] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
About this Structure
2b4g is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.
See Also
Reference
- Arakaki TL, Buckner FS, Gillespie JR, Malmquist NA, Phillips MA, Kalyuzhniy O, Luft JR, Detitta GT, Verlinde CL, Van Voorhis WC, Hol WG, Merritt EA. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies. Mol Microbiol. 2008 Apr;68(1):37-50. Epub 2008 Feb 26. PMID:18312275 doi:10.1111/j.1365-2958.2008.06131.x
