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2e6f

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[[Image:2e6f.png|left|200px]]
 
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{{STRUCTURE_2e6f| PDB=2e6f | SCENE= }}
{{STRUCTURE_2e6f| PDB=2e6f | SCENE= }}
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===Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate===
===Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate===
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==Function==
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[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
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==About this Structure==
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[[2e6f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6F OCA].
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(as it appears on PubMed at http://www.pubmed.gov), where 018808149 is the PubMed ID number.
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{{ABSTRACT_PUBMED_018808149}}
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==About this Structure==
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==See Also==
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[[2e6f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6F OCA].
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*[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:018808149</ref><references group="xtra"/>
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<ref group="xtra">PMID:018808149</ref><references group="xtra"/><references/>
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[[Category: Dihydroorotate oxidase]]
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[[Category: Trycr]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Aoki, T.]]
[[Category: Aoki, T.]]
[[Category: Harada, S.]]
[[Category: Harada, S.]]

Revision as of 08:12, 16 April 2014

Template:STRUCTURE 2e6f

Contents

Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate

Function

[PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.

About this Structure

2e6f is a 2 chain structure with sequence from Trycr. Full crystallographic information is available from OCA.

See Also

Reference

  • Inaoka DK, Sakamoto K, Shimizu H, Shiba T, Kurisu G, Nara T, Aoki T, Kita K, Harada S. Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction. Biochemistry. 2008 Oct 14;47(41):10881-91. Epub 2008 Sep 23. PMID:18808149 doi:10.1021/bi800413r

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