4e2i
From Proteopedia
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{{STRUCTURE_4e2i| PDB=4e2i | SCENE= }} | {{STRUCTURE_4e2i| PDB=4e2i | SCENE= }} | ||
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===The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase=== | ===The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase=== | ||
| + | {{ABSTRACT_PUBMED_22700977}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/DPOA2_HUMAN DPOA2_HUMAN]] May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[4e2i]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2I OCA]. | [[4e2i]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2I OCA]. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[DNA polymerase|DNA polymerase]] | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022700977</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Simian virus 40]] | [[Category: Simian virus 40]] | ||
Revision as of 04:58, 28 August 2013
Contents |
The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase
Template:ABSTRACT PUBMED 22700977
Function
[DPOA2_HUMAN] May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).
About this Structure
4e2i is a 23 chain structure with sequence from Homo sapiens and Simian virus 40. Full crystallographic information is available from OCA.
See Also
Reference
- Zhou B, Arnett DR, Yu X, Brewster A, Sowd GA, Xie CL, Vila S, Gai D, Fanning E, Chen XS. Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J Biol Chem. 2012 Aug 3;287(32):26854-66. doi: 10.1074/jbc.M112.363655. Epub 2012, Jun 14. PMID:22700977 doi:10.1074/jbc.M112.363655
