3b12

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3b12.jpg|left|200px]]
 
- 
{{STRUCTURE_3b12| PDB=3b12 | SCENE= }}
{{STRUCTURE_3b12| PDB=3b12 | SCENE= }}
- 
===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate===
===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate===
 +
{{ABSTRACT_PUBMED_22674735}}
-
{{ABSTRACT_PUBMED_22674735}}
+
==Function==
 +
[[http://www.uniprot.org/uniprot/DEHA_BURSP DEHA_BURSP]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1]<ref>PMID:19218394</ref>
==About this Structure==
==About this Structure==
Line 11: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:022674735</ref><references group="xtra"/>
+
<ref group="xtra">PMID:022674735</ref><references group="xtra"/><references/>
[[Category: Burkholderia sp.]]
[[Category: Burkholderia sp.]]
[[Category: Haloacetate dehalogenase]]
[[Category: Haloacetate dehalogenase]]

Revision as of 09:04, 19 June 2013

Template:STRUCTURE 3b12

Contents

Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate

Template:ABSTRACT PUBMED 22674735

Function

[DEHA_BURSP] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1][1]

About this Structure

3b12 is a 2 chain structure with sequence from Burkholderia sp.. Full crystallographic information is available from OCA.

Reference

  • Nakayama T, Kamachi T, Jitsumori K, Omi R, Hirotsu K, Esaki N, Kurihara T, Yoshizawa K. Substrate Specificity of Fluoroacetate Dehalogenase: An Insight from Crystallographic Analysis, Fluorescence Spectroscopy, and Theoretical Computations. Chemistry. 2012 Jun 1. doi: 10.1002/chem.201103369. PMID:22674735 doi:10.1002/chem.201103369
  1. Jitsumori K, Omi R, Kurihara T, Kurata A, Mihara H, Miyahara I, Hirotsu K, Esaki N. X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1. J Bacteriol. 2009 Apr;191(8):2630-7. Epub 2009 Feb 13. PMID:19218394 doi:10.1128/JB.01654-08

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools