3b12
From Proteopedia
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{{STRUCTURE_3b12| PDB=3b12 | SCENE= }} | {{STRUCTURE_3b12| PDB=3b12 | SCENE= }} | ||
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===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate=== | ===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate=== | ||
+ | {{ABSTRACT_PUBMED_22674735}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/DEHA_BURSP DEHA_BURSP]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1]<ref>PMID:19218394</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:022674735</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022674735</ref><references group="xtra"/><references/> |
[[Category: Burkholderia sp.]] | [[Category: Burkholderia sp.]] | ||
[[Category: Haloacetate dehalogenase]] | [[Category: Haloacetate dehalogenase]] |
Revision as of 09:04, 19 June 2013
Contents |
Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate
Template:ABSTRACT PUBMED 22674735
Function
[DEHA_BURSP] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1][1]
About this Structure
3b12 is a 2 chain structure with sequence from Burkholderia sp.. Full crystallographic information is available from OCA.
Reference
- Nakayama T, Kamachi T, Jitsumori K, Omi R, Hirotsu K, Esaki N, Kurihara T, Yoshizawa K. Substrate Specificity of Fluoroacetate Dehalogenase: An Insight from Crystallographic Analysis, Fluorescence Spectroscopy, and Theoretical Computations. Chemistry. 2012 Jun 1. doi: 10.1002/chem.201103369. PMID:22674735 doi:10.1002/chem.201103369
- ↑ Jitsumori K, Omi R, Kurihara T, Kurata A, Mihara H, Miyahara I, Hirotsu K, Esaki N. X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1. J Bacteriol. 2009 Apr;191(8):2630-7. Epub 2009 Feb 13. PMID:19218394 doi:10.1128/JB.01654-08