Hox protein

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<scene name='Sandbox_Reserved_169/Scr_recognition_helix/1'>Scr binds the major groove</scene>
<scene name='Sandbox_Reserved_169/Scr_recognition_helix/1'>Scr binds the major groove</scene>
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<scene name='Sandbox_Reserved_169/Scr_ypwm_motif/1'>YPWM motif</scene>
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<scene name='Sandbox_Reserved_169/Scr_ypwm_motif/2'>YPWM motif</scene>

Revision as of 20:26, 30 June 2012

This Sandbox is Reserved from 22 April 2012, through 31 August 2012 for use in the course "Protein DNA" taught by Remo_Rohs at the La Canada High School, USA. This reservation includes Sandbox Reserved 169 through Sandbox Reserved 170.
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Hox-DNA Recognition

Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).
Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).

Important for embryonic development across species. Recognize DNA with high binding specificity. 8 Drosophila Hox proteins. Bind with a co-factor. Shows crystal structure of Scr-Exd-DNA ternary complex.

Latent specificity of Hox proteins (cite).
Latent specificity of Hox proteins (cite).
</StructureSection>

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