3ugc
From Proteopedia
(Difference between revisions)
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===Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594=== | ===Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594=== | ||
| + | {{ABSTRACT_PUBMED_22684457}} | ||
==About this Structure== | ==About this Structure== | ||
[[3ugc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UGC OCA]. | [[3ugc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UGC OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022684457</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
Revision as of 05:11, 29 August 2012
Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594
Template:ABSTRACT PUBMED 22684457
About this Structure
3ugc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Andraos R, Qian Z, Bonenfant D, Rubert J, Vangrevelinghe E, Scheufler C, Marque F, Regnier CH, De Pover A, Ryckelynck H, Bhagwat N, Koppikar P, Goel A, Wyder L, Tavares G, Baffert F, Pissot-Soldermann C, Manley PW, Gaul C, Voshol H, Levine RL, Sellers WR, Hofmann F, Radimerski T. Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent. Cancer Discov. 2012 Jun;2(6):512-23. Epub 2012 May 3. PMID:22684457 doi:10.1158/2159-8290.CD-11-0324
