3te4
From Proteopedia
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{{STRUCTURE_3te4| PDB=3te4 | SCENE= }} | {{STRUCTURE_3te4| PDB=3te4 | SCENE= }} | ||
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===Crystal structure of dopamine N Acetyltransferase in complex with acetyl-COA from Drosophila Melanogaster=== | ===Crystal structure of dopamine N Acetyltransferase in complex with acetyl-COA from Drosophila Melanogaster=== | ||
| + | {{ABSTRACT_PUBMED_22716280}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DNAT_DROME DNAT_DROME]] Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.<ref>PMID:8901578</ref> <ref>PMID:9703021</ref> <ref>PMID:7498465</ref> | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3te4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3te4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TE4 OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:022716280</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022716280</ref><references group="xtra"/><references/> |
| - | [[Category: | + | [[Category: Drome]] |
[[Category: Cheng, K C.]] | [[Category: Cheng, K C.]] | ||
[[Category: Huang, S H.]] | [[Category: Huang, S H.]] | ||
Revision as of 14:17, 12 March 2014
Contents |
Crystal structure of dopamine N Acetyltransferase in complex with acetyl-COA from Drosophila Melanogaster
Template:ABSTRACT PUBMED 22716280
Function
[DNAT_DROME] Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.[1] [2] [3]
About this Structure
3te4 is a 1 chain structure with sequence from Drome. Full crystallographic information is available from OCA.
Reference
- Cheng KC, Liao JN, Lyu PC. Crystal Structure of Dopamine N-Acetyltransferase/Acetyl Coenzyme A Complex Provide Insights into the Catalytic Mechanism. Biochem J. 2012 Jun 21. PMID:22716280 doi:10.1042/BJ20120520
- ↑ Hintermann E, Grieder NC, Amherd R, Brodbeck D, Meyer UA. Cloning of an arylalkylamine N-acetyltransferase (aaNAT1) from Drosophila melanogaster expressed in the nervous system and the gut. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12315-20. PMID:8901578
- ↑ Brodbeck D, Amherd R, Callaerts P, Hintermann E, Meyer UA, Affolter M. Molecular and biochemical characterization of the aaNAT1 (Dat) locus in Drosophila melanogaster: differential expression of two gene products. DNA Cell Biol. 1998 Jul;17(7):621-33. PMID:9703021
- ↑ Hintermann E, Jeno P, Meyer UA. Isolation and characterization of an arylalkylamine N-acetyltransferase from Drosophila melanogaster. FEBS Lett. 1995 Nov 13;375(1-2):148-50. PMID:7498465
