1ikv
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | [[1ikv]] is a 2 chain structure | + | [[1ikv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IKV OCA]. |
==See Also== | ==See Also== |
Revision as of 15:00, 20 October 2012
Contents |
K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz
Template:ABSTRACT PUBMED 11895437
About this Structure
1ikv is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Lindberg J, Sigurdsson S, Lowgren S, Andersson HO, Sahlberg C, Noreen R, Fridborg K, Zhang H, Unge T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Eur J Biochem. 2002 Mar;269(6):1670-7. PMID:11895437
- Udier-Blagovic M, Tirado-Rives J, Jorgensen WL. Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. J Med Chem. 2004 Apr 22;47(9):2389-92. PMID:15084137 doi:10.1021/jm0303507