1a1d
From Proteopedia
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| - | [[Image:1a1d.gif|left|200px]] | + | [[Image:1a1d.gif|left|200px]] |
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| - | '''YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY''' | + | {{Structure |
| + | |PDB= 1a1d |SIZE=350|CAPTION= <scene name='initialview01'>1a1d</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1A1D is a [ | + | 1A1D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A1D OCA]. |
==Reference== | ==Reference== | ||
| - | Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family., Krapp S, Kelly G, Reischl J, Weinzierl RO, Matthews S, Nat Struct Biol. 1998 Feb;5(2):110-4. PMID:[http:// | + | Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family., Krapp S, Kelly G, Reischl J, Weinzierl RO, Matthews S, Nat Struct Biol. 1998 Feb;5(2):110-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9461075 9461075] |
[[Category: DNA-directed RNA polymerase]] | [[Category: DNA-directed RNA polymerase]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
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[[Category: yeast]] | [[Category: yeast]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:51:30 2008'' |
Revision as of 07:51, 20 March 2008
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| Activity: | DNA-directed RNA polymerase, with EC number 2.7.7.6 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY
Overview
RNA polymerase II subunit RPB8 is an essential subunit that is highly conserved throughout eukaryotic evolution and is present in all three types of nuclear RNA polymerases. We report the first high resolution structural insight into eukaryotic RNA polymerase architecture with the solution structure of RPB8 from Saccharomyces cerevisiae. It consists of an eight stranded, antiparallel beta-barrel, four short helical regions and a large, unstructured omega-loop. The strands are connected in classic Greek-key fashion. The overall topology is unusual and contains a striking C2 rotational symmetry. Furthermore, it is most likely a novel associate of the oligonucleotide/oligosaccharide (OB) binding protein class.
About this Structure
1A1D is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family., Krapp S, Kelly G, Reischl J, Weinzierl RO, Matthews S, Nat Struct Biol. 1998 Feb;5(2):110-4. PMID:9461075
Page seeded by OCA on Thu Mar 20 09:51:30 2008
