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1a7h
From Proteopedia
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| - | [[Image:1a7h.gif|left|200px]] | + | [[Image:1a7h.gif|left|200px]] |
| - | + | ||
| - | '''GAMMA S CRYSTALLIN C-TERMINAL DOMAIN''' | + | {{Structure |
| + | |PDB= 1a7h |SIZE=350|CAPTION= <scene name='initialview01'>1a7h</scene>, resolution 2.56Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= CRYGS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus]) | ||
| + | }} | ||
| + | |||
| + | '''GAMMA S CRYSTALLIN C-TERMINAL DOMAIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1A7H is a [ | + | 1A7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7H OCA]. |
==Reference== | ==Reference== | ||
| - | The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:[http:// | + | The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9681865 9681865] |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: multigene family]] | [[Category: multigene family]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:54:00 2008'' |
Revision as of 07:54, 20 March 2008
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| , resolution 2.56Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | CRYGS (Bos taurus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
GAMMA S CRYSTALLIN C-TERMINAL DOMAIN
Overview
The 2-domain gammaS-crystallin, a highly conserved early evolutionary off-shoot of the gamma-crystallin family, is located in the water-rich region of eye lenses. The expressed C-terminal domain, gammaS-C, has been crystallized and the 2.56 A X-ray structure determined. There are two domains in the asymmetric unit which pair about a distorted twofold axis. One of the domains has an altered conformation in a highly conserved region of the protein, the tyrosine corner. The distorted gammaS-C dimer of domains is compared with the highly symmetrical, equivalent recombinant dimer of C-terminal domains from gammaB-crystallin. Sequence changes close to the interface, that distinguish gammaS from the other gamma-crystallins, are examined in order to evaluate their role in symmetrical domain pairing.
About this Structure
1A7H is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:9681865
Page seeded by OCA on Thu Mar 20 09:54:00 2008
