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4g5p

From Proteopedia

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m (Protected "4g5p" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4g5p.jpg|left|200px]]
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The entry 4g5p is ON HOLD
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{{STRUCTURE_4g5p| PDB=4g5p | SCENE= }}
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Authors: Solca, F., Dahl, G., Zoephel, A., Bader, G., Sanderson, M., Klein, C., Kraemer, O., Himmelsbach, F., Haaksma, E., Adolf, G.R.
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===Crystal structure of EGFR kinase T790M in complex with BIBW2992===
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Description: Crystal structure of EGFR kinase T790M in complex with BIBW2992
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{{ABSTRACT_PUBMED_22888144}}
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==About this Structure==
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[[4g5p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5P OCA].
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==Reference==
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<ref group="xtra">PMID:022888144</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Adolf, G R.]]
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[[Category: Bader, G.]]
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[[Category: Dahl, G.]]
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[[Category: Haaksma, E.]]
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[[Category: Himmelsbach, F.]]
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[[Category: Klein, C.]]
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[[Category: Kraemer, O.]]
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[[Category: Sanderson, M.]]
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[[Category: Solca, F.]]
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[[Category: Zoephel, A.]]
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[[Category: Egf receptor kinase mutant t790m]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:12, 29 August 2012

Image:4g5p.jpg

Template:STRUCTURE 4g5p

Crystal structure of EGFR kinase T790M in complex with BIBW2992

Template:ABSTRACT PUBMED 22888144

About this Structure

4g5p is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Solca F, Dahl G, Zoephel A, Bader G, Sanderson M, Klein C, Kraemer O, Himmelsbach F, Haaksma E, Adolf GR. Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. J Pharmacol Exp Ther. 2012 Aug 10. PMID:22888144 doi:10.1124/jpet.112.197756

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OCA

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