3iit

From Proteopedia

Revision as of 09:26, 25 July 2012 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 09:26, 25 July 2012 (edit) (undo) OCA (Talk | contribs) m (Protected "3iit" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 09:26, 25 July 2012

proteopedia linkproteopedia link

Template:STRUCTURE 3iit

Contents 1 Factor XA in complex with a cis-1,2-diaminocyclohexane derivative 2 About this Structure 3 See Also 4 Reference

Factor XA in complex with a cis-1,2-diaminocyclohexane derivative

Template:ABSTRACT PUBMED 19900814

About this Structure

3iit is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Factor Xa

Reference

• Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024