1zxb

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Revision as of 13:12, 25 July 2012

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Template:STRUCTURE 1zxb

Contents 1 Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives 2 About this Structure 3 See Also 4 Reference

Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives

Template:ABSTRACT PUBMED 16198563

About this Structure

1zxb is a 2 chain structure of Enoyl-Acyl-Carrier Protein Reductase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

• Enoyl-Acyl-Carrier Protein Reductase

Reference

• Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR Jr, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC. Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5247-52. Epub 2005 Sep 29. PMID:16198563 doi:10.1016/j.bmcl.2005.08.044