1awc
From Proteopedia
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| - | [[Image:1awc.gif|left|200px]] | + | [[Image:1awc.gif|left|200px]] |
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| - | '''MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA''' | + | {{Structure |
| + | |PDB= 1awc |SIZE=350|CAPTION= <scene name='initialview01'>1awc</scene>, resolution 2.150Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= GABP ALPHA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), GABP BETA 1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]) | ||
| + | }} | ||
| + | |||
| + | '''MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1AWC is a [ | + | 1AWC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AWC OCA]. |
==Reference== | ==Reference== | ||
| - | The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA., Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C, Science. 1998 Feb 13;279(5353):1037-41. PMID:[http:// | + | The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA., Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C, Science. 1998 Feb 13;279(5353):1037-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9461436 9461436] |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Batchelor, A H.]] | [[Category: Batchelor, A H.]] | ||
[[Category: Wolberger, C.]] | [[Category: Wolberger, C.]] | ||
| - | [[Category: ankyrin | + | [[Category: ankyrin repeat]] |
[[Category: complex (transcription regulation/dna)]] | [[Category: complex (transcription regulation/dna)]] | ||
[[Category: dna-binding]] | [[Category: dna-binding]] | ||
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[[Category: transcription factor]] | [[Category: transcription factor]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:03:04 2008'' |
Revision as of 08:03, 20 March 2008
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| , resolution 2.150Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | GABP ALPHA (Mus musculus), GABP BETA 1 (Mus musculus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA
Overview
GA-binding protein (GABP) is a transcriptional regulator composed of two structurally dissimilar subunits. The alpha subunit contains a DNA-binding domain that is a member of the ETS family, whereas the beta subunit contains a series of ankyrin repeats. The crystal structure of a ternary complex containing a GABPalpha/beta ETS domain-ankyrin repeat heterodimer bound to DNA was determined at 2. 15 angstrom resolution. The structure shows how an ETS domain protein can recruit a partner protein using both the ETS domain and a carboxyl-terminal extension and provides a view of an extensive protein-protein interface formed by a set of ankyrin repeats. The structure also reveals how the GABPalpha ETS domain binds to its core GGA DNA-recognition motif.
About this Structure
1AWC is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA., Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C, Science. 1998 Feb 13;279(5353):1037-41. PMID:9461436
Page seeded by OCA on Thu Mar 20 10:03:04 2008
