Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1odf
From Proteopedia
| Line 21: | Line 21: | ||
[[Category: yeast protein]] | [[Category: yeast protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 15:50:31 2007'' |
Revision as of 13:45, 30 October 2007
|
STRUCTURE OF YGR205W PROTEIN.
Overview
The protein product of the YGR205w gene of Saccharomyces cerevisiae was, targeted as part of our yeast structural genomics project. YGR205w codes, for a small (290 amino acids) protein with unknown structure and function., The only recognizable sequence feature is the presence of a Walker A motif, (P loop) indicating a possible nucleotide binding/converting function. We, determined the three-dimensional crystal structure of Se-methionine, substituted protein using multiple anomalous diffraction. The structure, revealed a well known mononucleotide fold and strong resemblance to the, structure of small metabolite phosphorylating enzymes such as pantothenate, and phosphoribulo kinase. Biochemical experiments show that YGR205w binds, specifically ATP and, less tightly, ADP. The structure also ... [(full description)]
About this Structure
1ODF is a [Single protein] structure of sequence from [Saccharomyces cerevisiae] with SO4 and GOL as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase., de La Sierra-Gallay IL, Collinet B, Graille M, Quevillon-Cheruel S, Liger D, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Zhou CZ, Sorel I, Ferrer JL, Poupon A, Janin J, van Tilbeurgh H, Proteins. 2004 Mar 1;54(4):776-83. PMID:14997573
Page seeded by OCA on Tue Oct 30 15:50:31 2007
