2nru

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Revision as of 14:00, 25 July 2012

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Template:STRUCTURE 2nru

Contents 1 Crystal structure of IRAK-4 2 About this Structure 3 See Also 4 Reference

Crystal structure of IRAK-4

Template:ABSTRACT PUBMED 17161373

About this Structure

2nru is a 4 chain structure of Interleukin-1 receptor-associated kinase 4 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Interleukin-1 receptor-associated kinase 4

Reference

• Wang Z, Liu J, Sudom A, Ayres M, Li S, Wesche H, Powers JP, Walker NP. Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. Structure. 2006 Dec;14(12):1835-44. PMID:17161373 doi:10.1016/j.str.2006.11.001
• Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121