3cds
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3cds]] is a 2 chain structure | + | [[3cds]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CDS OCA]. |
==See Also== | ==See Also== | ||
Revision as of 06:51, 20 October 2012
Contents |
Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue)
Template:ABSTRACT PUBMED 19053776
About this Structure
3cds is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Montanari R, Saccoccia F, Scotti E, Crestani M, Godio C, Gilardi F, Loiodice F, Fracchiolla G, Laghezza A, Tortorella P, Lavecchia A, Novellino E, Mazza F, Aschi M, Pochetti G. Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design. J Med Chem. 2008 Dec 25;51(24):7768-76. PMID:19053776 doi:10.1021/jm800733h
- Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. Epub 2001 Nov 6. PMID:11698662 doi:10.1073/pnas.241410198
Categories: Homo sapiens | Mazza, F. | Montanari, R. | Pochetti, G. | Activator | Bundle of alpha-helices and a small four-stranded beta-sheet | Diabetes mellitus | Disease mutation | Dna-binding | Metal-binding | Nucleus | Obesity | Phosphoprotein | Receptor | Transcription | Transcription regulation | Zinc-finger
