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2gtm

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Image:2gtm.png

Template:STRUCTURE 2gtm

Contents

Mutated Mouse P38 MAP Kinase Domain in complex with Inhibitor PG-892579

Template:ABSTRACT PUBMED 16750367

About this Structure

2gtm is a 1 chain structure of Mitogen-activated protein kinase with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Sabat M, Vanrens JC, Clark MP, Brugel TA, Maier J, Bookland RG, Laufersweiler MJ, Laughlin SK, Golebiowski A, De B, Hsieh LC, Walter RL, Mekel MJ, Janusz MJ. The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4360-5. Epub 2006 Jun 5. PMID:16750367 doi:10.1016/j.bmcl.2006.05.050

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OCA

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