1bj7

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[[Image:1bj7.gif|left|200px]]<br /><applet load="1bj7" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1bj7.gif|left|200px]]
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caption="1bj7, resolution 1.8&Aring;" />
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'''BOVINE LIPOCALIN ALLERGEN BOS D 2'''<br />
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{{Structure
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|PDB= 1bj7 |SIZE=350|CAPTION= <scene name='initialview01'>1bj7</scene>, resolution 1.8&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''BOVINE LIPOCALIN ALLERGEN BOS D 2'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1BJ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].
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1BJ7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].
==Reference==
==Reference==
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Probing the molecular basis of allergy. three-dimensional structure of the bovine lipocalin allergen Bos d 2., Rouvinen J, Rautiainen J, Virtanen T, Zeiler T, Kauppinen J, Taivainen A, Mantyjarvi R, J Biol Chem. 1999 Jan 22;274(4):2337-43. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9891000 9891000]
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Probing the molecular basis of allergy. three-dimensional structure of the bovine lipocalin allergen Bos d 2., Rouvinen J, Rautiainen J, Virtanen T, Zeiler T, Kauppinen J, Taivainen A, Mantyjarvi R, J Biol Chem. 1999 Jan 22;274(4):2337-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9891000 9891000]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: lipocalin]]
[[Category: lipocalin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:55:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:11:49 2008''

Revision as of 08:11, 20 March 2008

Image:1bj7.gif


PDB ID 1bj7

Drag the structure with the mouse to rotate
, resolution 1.8Å
Coordinates: save as pdb, mmCIF, xml



BOVINE LIPOCALIN ALLERGEN BOS D 2


Overview

The three-dimensional structure of the major bovine allergen Bos d 2 has been determined by using x-ray diffraction at 1.8-A resolution. Structurally Bos d 2 is a member of the lipocalin family comprising proteins with transport functions. There is a flat small cavity inside the Bos d 2 protein core suitable for ligand binding, and it is possible that Glu115 and Asn37 inside the core are able to make hydrogen bonds with the ligand. Many allergens from different animals belong to the lipocalin family. The amino acid residue similarities between these lipocalins indicate putative regions for IgE binding. Comparison with the available allergen structures from other sources suggests that these allergens are roughly the same size and that their shape is more spherical than elliptical.

About this Structure

1BJ7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Probing the molecular basis of allergy. three-dimensional structure of the bovine lipocalin allergen Bos d 2., Rouvinen J, Rautiainen J, Virtanen T, Zeiler T, Kauppinen J, Taivainen A, Mantyjarvi R, J Biol Chem. 1999 Jan 22;274(4):2337-43. PMID:9891000

Page seeded by OCA on Thu Mar 20 10:11:49 2008

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