1ptu

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Revision as of 20:39, 25 July 2012

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Template:STRUCTURE 1ptu

Contents 1 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2) 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)

Template:ABSTRACT PUBMED 7540771

About this Structure

1ptu is a 2 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.

See Also

• Proten tyrosine phosphatase
• Tyrosine phosphatase

Reference

• Jia Z, Barford D, Flint AJ, Tonks NK. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science. 1995 Jun 23;268(5218):1754-8. PMID:7540771
• Zhang YL, Yao ZJ, Sarmiento M, Wu L, Burke TR Jr, Zhang ZY. Thermodynamic study of ligand binding to protein-tyrosine phosphatase 1B and its substrate-trapping mutants. J Biol Chem. 2000 Nov 3;275(44):34205-12. PMID:10952978 doi:10.1074/jbc.M004490200