3g9n

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Revision as of 20:57, 25 July 2012

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Template:STRUCTURE 3g9n

Contents 1 JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one 2 About this Structure 3 See Also 4 Reference

JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one

Template:ABSTRACT PUBMED 19361991

About this Structure

3g9n is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase

Reference

• Cao J, Gao H, Bemis G, Salituro F, Ledeboer M, Harrington E, Wilke S, Taslimi P, Pazhanisamy S, Xie X, Jacobs M, Green J. Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg Med Chem Lett. 2009 May 15;19(10):2891-5. Epub 2009 Mar 17. PMID:19361991 doi:10.1016/j.bmcl.2009.03.043