2c8y

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Revision as of 23:13, 25 July 2012

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Template:STRUCTURE 2c8y

Contents 1 THROMBIN INHIBITORS 2 About this Structure 3 See Also 4 Reference

THROMBIN INHIBITORS

Template:ABSTRACT PUBMED 16480269

About this Structure

2c8y is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hirudin
• Thrombin

Reference

• Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:16480269 doi:10.1021/jm050850v