2pjt
From Proteopedia
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Revision as of 02:43, 26 July 2012
Contents |
Crystal structure of the catalytic domain of MMP-13 complexed with WAY-344
Template:ABSTRACT PUBMED 17606376
About this Structure
2pjt is a 4 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Huang A, Joseph-McCarthy D, Lovering F, Sun L, Wang W, Xu W, Zhu Y, Cui J, Zhang Y, Levin JI. Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket. Bioorg Med Chem. 2007 Sep 15;15(18):6170-81. Epub 2007 Jun 20. PMID:17606376 doi:10.1016/j.bmc.2007.06.031
Categories: Homo sapiens | Huang, A. | Levin, J I. | Lovering, F. | Mosyak, L. | Xu, Z. | Collagen degradation | Collagenase | Disease mutation | Extracellular matrix | Glycoprotein | Hydrolase | Hydrophobic s1s' | Hydroxamate | Metal-binding | Metalloprotease | Mmp-13 | Mmp | P1' group | Secreted | Zinc chelator | Zymogen
