1csn

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[[Image:1csn.gif|left|200px]]<br /><applet load="1csn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1csn.gif|left|200px]]
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caption="1csn, resolution 2.0&Aring;" />
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'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP'''<br />
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{{Structure
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|PDB= 1csn |SIZE=350|CAPTION= <scene name='initialview01'>1csn</scene>, resolution 2.0&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1CSN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSN OCA].
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1CSN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSN OCA].
==Reference==
==Reference==
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Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7889932 7889932]
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Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7889932 7889932]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: phosphotransferase]]
[[Category: phosphotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:09:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:28:23 2008''

Revision as of 08:28, 20 March 2008

Image:1csn.gif


PDB ID 1csn

Drag the structure with the mouse to rotate
, resolution 2.0Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP


Overview

The structure of a truncated variant of casein kinase-1 from Schizosaccharomyces pombe, has been determined in complex with MgATP at 2.0 A resolution. The model resembles the 'closed', ATP-bound conformations of the cyclin-dependent kinase 2 and the cAMP-dependent protein kinase, with clear differences in the structure of surface loops that impart unique features to casein kinase-1. The structure is of unphosphorylated, active conformation of casein kinase-1 and the peptide-binding site is fully accessible to substrate.

About this Structure

1CSN is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:7889932

Page seeded by OCA on Thu Mar 20 10:28:23 2008

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