3h4g

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Revision as of 05:22, 26 July 2012

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Template:STRUCTURE 3h4g

Contents 1 Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity 2 About this Structure 3 See Also 4 Reference

Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity

Template:ABSTRACT PUBMED 16107153

About this Structure

3h4g is a 1 chain structure of Alcohol dehydrogenase and Aldose Reductase with sequence from Sus scrofa. This structure supersedes the now removed PDB entry 2ao0. Full crystallographic information is available from OCA.

See Also

• Alcohol dehydrogenase
• Aldose Reductase

Reference

• El-Kabbani O, Carbone V, Darmanin C, Oka M, Mitschler A, Podjarny A, Schulze-Briese C, Chung RP. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. J Med Chem. 2005 Aug 25;48(17):5536-42. PMID:16107153 doi:10.1021/jm050412o